Natural Products and Their Derivatives with Antibacterial, Antioxidant and Anticancer Activities

Isocorydine derivatives and their anticancer activities.

In order to improve the anticancer activity of isocorydine (ICD), ten isocorydine derivatives were prepared through chemical structure modifications, and their in vitro and in vivo activities were experimentally investigated. 8-Amino-isocorydine (8) and 6a,7-dihydrogen-isocorydione (10) could inhibit the growth of human lung (A549), gastric (SGC7901) and liver (HepG2) cancer cell lines in vitro...

Natural Based Anticancer Drugs and Their Worthiness

Antibacterial, Antioxidant, and Anticancer Activities of Biosynthesized Selenium Nanoparticles Using Two Indigenous Halophilic Bacteria

Background & Aims of the Study: Selenium is an essential nutritional material used for the important functions of the human body. The issue of the production of selenium nanoparticles (SeNPs) was investigated in various fields, such as anticancer, antioxidant, and antibacterial activities. Materials and Methods: In order to study antibacterial activity, the nutrient broth medium containing ...

Antioxidant and Antibacterial Activities of Some Natural Polyphenols

* “Aurel Vlaicu” University of Arad, Research, Development & Innovation in Technical and Natural Sciences Institute, 2, E. Drăgoi Str., 310330, Arad, Romania ** “Gheorghe Asachi” Technical University, Faculty of Chemical Engineering and Environmental Protection, 71 A, Mangeron Blvd., 700050 Iasi, Romania *** University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, 3-5, Mănăştur...

Telomerase Inhibitors from Natural Products and Their Anticancer Potential

Telomeres and telomerase are nowadays exploring traits on targets for anticancer therapy. Telomerase is a unique reverse transcriptase enzyme, considered as a primary factor in almost all cancer cells, which is mainly responsible to regulate the telomere length. Hence, telomerase ensures the indefinite cell proliferation during malignancy-a hallmark of cancer-and this distinctive feature has pr...